This year marks an important anniversary. In 1807, the Russian Empire and the young American Republic agreed to establish diplomatic relations. Soon after, Russia's first envoy, Alexander Dashkov, arrived in Washington, and John Quincy Adams traveled to St. Petersburg. Since this modest beginning, our relations, at their best and worst, have borne out de Tocqueville's prophecy that America and Russia are "marked out by the will of Heaven to sway the destinies of half the globe." Today, with the Cold War and immediate post-Soviet transition behind us, we face a new world in which an effective U.S.-Russian relationship is central to addressing many global challenges.