I've been researching different parts of the wider MENA region as an "outsider-insider" for some two decades. A few days after the Biden administration takes office, it will be the 10th anniversary of the Egyptian revolutionary uprising of 2011 – an uprising I experienced, during which Joe Biden was Vice-President. A decade on from that, the region's politics are now deeply impacted by a new geopolitical 'cold war' – the MENA's own sluggish struggle between two axes struggling for dominance in the region, alongside older rivalries. Against the backdrop of those enmities, one may ask: what's the likely meaning of a Biden-Harris administration for the region itself? What can American allies inside, and outside, the region expect? A decade on from the uprising, can activists on the ground expect anything new?